郭爱克
郭爱克
博导 | 生物工程
工作单位
中国科学院生物物理研究所
咨询量
0
满意度
100%

个人简介

1988— 中科院生物物理所研究所研究员 1999— 中国科学院神经科学研究所高级研究员 1982.11.30—1984.06.30 德国马普学会生物控制论研究所访问学者 1984—1991 中科院生物物理研究所视觉信息加工研究室主任 1991—1995 中科院生物物理所研究所神经生物学室主任 1999.11— 中国科学院神经科学研究所学习记忆实验室高级研究员 2005— 脑与认知科学国家重点实验室学术委员会主任 2003—2008 中国科学院神经科学研究所副所长 1999—2001 亚太IBRO理事 2001— Editorial board Journal of Integrative neuroscience; 2008— Associate Editors of BMC Neuroscience 2003年当选为中国科学院院士

科研成果

(1) 脑功能联结图谱计划(中国科学院战略性先导科技专项),主持,2012 - 2016 (2)个体抉择与群体抉择的神经生物学基础(基金委重点项目),主持,2011-12--2015-12 (2) 智力的神经基础(973),参与,2011-07--2015-07

近期动态

1.Liu, H., Zhou, B., Yan, W., Lei, Z., Zhao, X., Zhang, K., and Guo, A. (2014) Astrocyte-like glial cells physiologically regulate olfactory processing through the modification of ORN-PN synaptic strength in Drosophila. Eur. J. Neurosci. 40: 2744-2754. 2.Lei, Z., Chen, K., Li, H., Liu, H., and Guo, A.(2013) The GABA system regulates the sparse coding of odors in the mushroom bodies of Drosophila. Biochem. Biophys. Res. Commun. 436: 35-40. 3.Li, H., Li, Y., Lei, Z., Wang, K., and Guo, A. (2013) Transformation of odor selectivity from projection neurons to single mushroom body neurons mapped with dual-color calcium imaging. Proc. Natl. Acad. Sci. USA. 110: 12084-12089. 4.Yang, X., and Guo, A. (2013) Distinct acute zones for visual stimuli in different visual tasks in Drosophila. PLoS One 8: e61313. 5.Wu, Y., Ren, Q., Li, H., and Guo, A. (2012) The GABAergic anterior paired lateral neurons facilitate olfactory reversal learning in Drosophila. Learn. Mem. 19: 478-486. 6.Ren, Q., Li, H., Wu, Y., Ren, J., and Guo, A.(2012)A gabaergic inhibitory neural circuit regulates visual reversal learning in drosophila. J. Neurosci. 32:11524 –11538 7.Chen, B., Liu, H., Ren, J., and Guo, A. (2012) Mutation of Drosophila dopamine receptor DopR leads to male-male courtship behavior. Biochem Biophys Res Commun. 423: 557-563. 8. Li, X., Yu, F., and Guo, A. (2009) Sleep Deprivation Specifically Impairs Short-term Olfactory Memory in Drosophila. Sleep 32: 1417-1424. 9. Liu, T., Dartevelle, L., Yuan, C., Wei, H., Wang, Y., Ferveur, J, and Guo, A. (2009) Reduction of dopamine level enhances the attractiveness of male Drosophila to other males. PLoS ONE 4: e4574. 10. Lu, S., Fang, J., Guo, A., and Peng, Y. (2009) Impact of network topology on decision-making. Neural Netw. 22: 30-40. 11. Liu, T., Dartevelle, L., Yuan, C., Wei, H., Wang, Y., Ferveur J., and Guo, A. (2008) Increased dopamine level enhances male-male courtship in Drosophila. J. Neurosci. 28: 5539-5546. 12. Xi, W., Peng, Y., Guo, J., Ye, Y., Zhang, K., Yu, F., and Guo, A. (2008) Mushroom bodies modulate salience-based selective fixation behavior in Drosophila. Eur. J. Neurosci., 27: 1441-1451. 13. Zhang, K., Guo, J., Peng, Y., Xi, W., and Guo, A. (2007) Dopamine-Mushroom Body Circuit Regulates Saliency-Based Decision-Making in Drosophila. Science 316: 1901-1904. 14. Peng, Y., Xi, W., Zhang, W., Zhang, K., and Guo, A. (2007) Experience Improves Feature Extraction in Drosophila. J. Neurosci. 27: 5139-5145. 15. Xu, S., Cang, C., Liu, X., Peng, Y., Ye, Y., Zhao, Z., and Guo, A. (2006) Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene. Genes Brain Behav. 5(8): 602-613. 16. Guo, J., and Guo, A. (2005) Crossmodal Interactions Between Olfactory and Visual Learning in Drosophila. Science 309: 307-310. 17. Zhou, X., Yuan, C., and Guo, A. (2005) Drosophila Olfactory Response Rhythms Require Clock Genes but Not Pigment Dispersing Factor or Lateral Neurons. J. Biol. Rhythm. 20: 237-244. 18. Ye, Y., Xi, W., Peng, Y., Wang, Y., and Guo, A. (2004) Long-term but not short-term blockade of dopamine release in Drosophila impairs orientation during flight in a visual attention paradigm. Eur. J. Neurosci. 20: 1001-1007. 19. Tang, S., and Guo, A. (2001) Choice behavior of Drosophila facing contradictory visual cues. Science, 294: 1543-1547.

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